Fig. 13.34 
The ear/y effects of therapy with a GnRH agonist in a girl with idiopathic central precocious puberty. 
Basal and peak concentrations following an intravenous 100µg/kg dose of GnRH, before and after the indicated period of treatment with a GnRH agonist Trp6Pro9Net-GnRH, are shown. Decreased levels of serum LH, FSH, and oestradiol are seen by the second week of treatment. Modified from Kaplan and Grumbach (1990), by courtesy of Williams and Wilkins Company.